apaflurane has been researched along with (9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (16.22) | 18.2507 |
| 2000's | 74 (66.67) | 29.6817 |
| 2010's | 18 (16.22) | 24.3611 |
| 2020's | 1 (0.90) | 2.80 |
| Authors | Studies |
|---|---|
| Leach, CL | 1 |
| Harrison, LI; Seale, JP | 1 |
| Hader, S; Kunkel, G; Matthys, H; Nowak, D | 1 |
| Davies, RJ; O'Connor, BJ; Stampone, P | 1 |
| Davies, RJ; Donnell, D; Grossman, AB; Thompson, PJ; Young, WF | 1 |
| Tashkin, DP | 2 |
| Chervinsky, P; Gross, G; Thompson, PJ; Vanden Burgt, J | 1 |
| Colice, GL; Dockhorn, R; Donnell, D; Harrison, LI; Soria, I | 1 |
| Ayres, JG; Simmons, JL; Stampone, P | 1 |
| Milanowski, J; Perrin, VL; Qualtrough, J | 1 |
| Newman, SP; Pitcairn, GR | 1 |
| Dean, NL | 1 |
| Buist, AS; Juniper, EF | 1 |
| Borgström, L | 1 |
| Leach, C | 1 |
| Aberle, DR; Colice, GL; Goldin, JG; Greaser, LE; Haywood, UM; Kleerup, EC; Sayre, JW; Simmons, MD; Suttorp, M; Tashkin, DP; Vanden Burgt, JA | 1 |
| Jackson, CM; Lipworth, BJ | 2 |
| Chrystyn, H | 1 |
| Ayres, JG | 1 |
| Pavord, ID | 1 |
| Farmer, IS; Herdman, MJ; Middle, M; Perri, VL; Savic, J | 1 |
| Chinet, T | 1 |
| Hu, C; Williams, RO | 2 |
| Magnussen, H | 1 |
| Muir, JF | 1 |
| Lipworth, BJ | 1 |
| Worth, H | 1 |
| Fairfax, AJ | 1 |
| Busse, WW; Donnell, D; Martin, RJ; Szefler, SJ; Vanden Burgt, JA | 1 |
| Aubier, M; Gans, SJ; Wettenger, R | 1 |
| Cohen, RM; Demedts, M; Fireman, P; Mol, SJ; Prenner, BM; Vincken, W | 1 |
| Ahrens, RC; Donnell, D; Han, SH; Lux, CR; Teresi, ME; Vanden Burgt, JA | 1 |
| Hajiro, T; Ishihara, K | 1 |
| Muir, JF; Pieters, WR; Worth, H | 1 |
| Arora, S; Le Bourgeois, M; Pedersen, S; Staab, D; Szefler, SJ; Van Essen-Zandvliet, E; Wahn, U; Warner, J | 1 |
| Currie, GP; Fowler, SJ; Lipworth, BJ | 1 |
| Arora, S; Le Bourgeois, M; Pedersen, S; Staab, D; Szefler, SJ; van Essen-Zandvliet, EE; Wahn, U; Warner, J | 1 |
| Duerden, M; Haughney, J; Moseley, C; Nicholls, C; Price, D | 1 |
| Boudreau, RJ; Davidson, PJ; Hasselquist, BE; Leach, CL | 1 |
| Bousquet, J; Cantini, L | 1 |
| Acerbi, D; Poli, G; Woodcock, A | 1 |
| Currie, GP; Fowler, SJ; Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM | 1 |
| Addlestone, R; Anderson, PB; Cantini, L; Jones, J; Langley, SJ; Mooney, P; Rossetti, A | 1 |
| Cantini, L; Kotasová, J; Rossetti, A; Sladek, K; Terl, M; Vondra, V | 1 |
| Brown, HM | 1 |
| Harrison, LI | 1 |
| Batty, L; Cantini, L; Masterson, C; Rossetti, A; Williams, A; Woodcock, A | 1 |
| De Jongste, JC; Hop, WC; Janssens, HM; Tiddens, HA | 1 |
| Gupta, A; Myrdal, PB; Stein, SW | 1 |
| Luskin, AT; Malone, DC | 1 |
| Asmus, MJ; Coowanitwong, I; Hochhaus, G; Khorsand, N; Kwon, SH | 1 |
| Diot, P; Khanjari, F; Koninck, JC; Lemarié, E; Magro, P | 1 |
| Boulet, LP; Cartier, A; Ernst, P; Larivée, P; Laviolette, M | 1 |
| Ayres, J; Crampton, M; Kinnersley, R | 1 |
| Branscheid, D; Einhaus, M; Harrison, LI; Holz, O; Jörres, RA; Kanniess, F; Magnussen, H; Nakashima, M; Richter, K; Welker, L; Zühlke, I | 1 |
| Donnell, D; Van Schayck, CP | 2 |
| Cole, CH; Foley, MP; Mitchell, JP; Nagel, MW | 1 |
| Abe, S; Nakamura, N; Saikai, T; Suzuki, K; Takeya, I; Tanaka, H; Tanaka, N; Tsunematsu, K | 1 |
| Dal Negro, RW; Guerriero, M; Micheletto, C; Tognella, S | 1 |
| Derom, E; Pauwels, RA | 1 |
| Kossack, WS; Nelson, HS; Silkoff, PE; Thongngarm, T | 1 |
| Mogalian, E; Myrdal, PB | 1 |
| Bergeron, C; Hamid, Q; Hauber, H; Migounov, V; Olivenstein, R; Taha, R | 1 |
| Brown, MB; Jones, SA; Martin, GP | 1 |
| Barnes, ML; Burns, P; Fardon, TC; Lipworth, BJ | 1 |
| Ohbayashi, H | 1 |
| Hayashi, N; Hirose, M; Horiguchi, T; Ito, T; Kondo, R; Miyazaki, J; Ohira, D; Sasaki, Y; Shiga, M; Tachikawa, S; Torigoe, H | 1 |
| Aoki, M; Fukao, T; Hosoi, K; Kondo, N; Matsui, E; Mikawa, H; Teramoto, T; Terauchi, Y; Tomita, Y | 1 |
| Wolthers, OD | 1 |
| Cantagrel, S; De Monte, M; De Muret, A; Diot, P; Dubus, JC; Goucher, A; Le Guellec, S; Le Pape, A; Majoral, C; Mezzi, K; Montharu, J; Vecellio, L | 1 |
| Hopkinson, P; Lipworth, BJ; McFarlane, L; Menzies, D; Nair, A | 1 |
| Barnes, M; Burns, P; Fardon, T; Lipworth, B; Menzies, D; Nair, A | 1 |
| Adachi, M; Inoue, H; Ishihara, K; Kato, R; Kudo, K; Masuda, K; Miyamoto, T; Morita, Y; Sakai, T; Takahashi, K | 1 |
| Adachi, M; Hirata, K; Ichinose, M; Kokubu, F; Ohbayashi, H; Ohta, K; Sano, Y; Tamura, G; Tohda, Y; Yasuba, H | 1 |
| Doi, S; Inoue, T; Kameda, M; Nishikido, T; Takamatu, I; Yoshida, Y | 1 |
| Gillissen, A; Oster, H; Richter, A | 1 |
| Criée, CP; Gillissen, A; Oster, H; Richter, A | 1 |
| Brown, MB; Jones, SA; Reid, ML | 3 |
| Damoiseaux, JG; Dompeling, E; Hendriks, HJ; Jöbsis, Q; Kester, AD; Rijkers, GT; Robroeks, CM; van de Kant, KD; van Vliet, D; Wodzig, WK | 1 |
| Bont, LJ; Ermers, MJ; Kimpen, JL; Rovers, MM; van Woensel, JB | 1 |
| Banno, M; Ibata, H; Matsushita, R; Niimi, T; Sato, S | 1 |
| Akazawa, K; Arakawa, M; Gejyo, F; Hasegawa, T; Koya, T; Ota, K; Sakagami, T; Sekikawa, T; Suzuki, E; Toyabe, S | 1 |
| Chin, K; Hirai, T; Ito, I; Jinnai, M; Matsumoto, H; Matsuoka, H; Mishima, M; Niimi, A; Oguma, T; Otsuka, K; Takeda, T; Takemura, M; Ueda, T; Yamaguchi, M | 1 |
| Acerbi, D; Bousquet, J; Monno, R; Nollevaux, F; Poli, G; Ramael, S | 1 |
| Colice, GL; Leach, CL | 1 |
| Eid, N; Morton, R | 1 |
| Barnes, N; Burden, A; Chisholm, A; Colice, G; Dorinsky, P; Hillyer, EV; Israel, E; Lee, AJ; Martin, RJ; Price, D; Roche, N; von Ziegenweidt, J | 1 |
| Walters, EG; Wolthers, OD | 1 |
| Chand, R; Ketai, L; Kuehl, PJ; Leach, CL; McDonald, JD; Norenberg, JP | 1 |
| Adachi, M; Ohbayashi, H | 1 |
| Church, T; Finlay, WH; Hoe, S; Lewis, D; Shemirani, FM; Vehring, R | 1 |
| Barion, F; Barnes, N; Burden, A; Chisholm, A; Colice, G; Dorinsky, P; Hillyer, EV; Israel, E; Lee, AJ; Martin, RJ; Polos, P; Price, D; Roche, N; von Ziegenweidt, J | 1 |
| Benaouda, F; Brown, MB; Jones, SA; Khengar, R; Reid, ML | 1 |
| Boyd, BJ; Gaisford, S; Ooi, J; Traini, D; Young, PM | 1 |
| Chan, HK; D'Sa, DJ; Lechuga-Ballesteros, D | 1 |
| Anderson, WJ; Lipworth, BJ; Manoharan, A; Short, PM; Williamson, PA | 1 |
| Chan, HK; Chen, Y; Church, T; Fletcher, DF; Lewis, D; Long, E; Traini, D; Young, PM | 1 |
| Chand, R; Kuehl, PJ; Leach, CL; McDonald, JD | 1 |
| Cilluffo, G; Ferrante, G; La Grutta, S; Malizia, V; Marchese, D; Montalbano, L | 1 |
| Bhambri, P; Church, TK; Elbayomy, S; Finlay, WH; Ivey, JW; Lewis, DA; McDermott, MT; Vehring, R | 1 |
| AbuRuz, S; Chrystyn, H; Said, AS | 1 |
| Liu, C; Liu, T; Yang, D | 1 |
14 review(s) available for apaflurane and (9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
| Article | Year |
|---|---|
Improved delivery of inhaled steroids to the large and small airways.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchi; Drug Delivery Systems; Humans; Hydrocarbons, Fluorinated; Lung; Nebulizers and Vaporizers; Particle Size; Pulmonary Alveoli; Radionuclide Imaging; Technetium | 1998 |
Effect of changing the fine particle mass of inhaled beclomethasone dipropionate on intrapulmonary deposition and pharmacokinetics.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Hydrocarbons, Fluorinated; Lung; Male; Middle Aged; Particle Size; Randomized Controlled Trials as Topic | 1998 |
[Changes in metered dose inhaler propellants].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Aerosol Propellants; Animals; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Respiratory Therapy | 2000 |
An overview of the clinical efficacy of HFA-BDP in asthma.
Topics: Administration, Topical; Aerosol Propellants; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Glucocorticoids; Humans; Hydrocarbons, Fluorinated | 2000 |
The comparative safety/efficacy ratio of HFA-BDP.
Topics: Administration, Topical; Aerosol Propellants; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Risk Assessment | 2000 |
A comparison of HFA-BDP Autohaler with budesonide Turbuhaler in asthma control of adult patients with mild to moderately severe disease.
Topics: Administration, Topical; Adult; Aerosol Propellants; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Budesonide; Chemistry, Pharmaceutical; Clinical Trials as Topic; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers | 2000 |
The relative clinical effectiveness of HFA-BDP and fluticasone propionate in asthma.
Topics: Administration, Topical; Aerosol Propellants; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Fluticasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated | 2000 |
HFA-BDP and its implications for the quiet zone.
Topics: Administration, Topical; Aerosol Propellants; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchi; Bronchography; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Tomography, X-Ray Computed | 2000 |
Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane-beclomethasone extrafine inhalation aerosol), in asthma.
Topics: Administration, Inhalation; Aerosol Propellants; Aerosols; Asthma; Beclomethasone; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2000 |
[Inhaled corticosteroids: first-line therapy in asthma].
Topics: Administration, Inhalation; Administration, Topical; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Budesonide; Clinical Trials as Topic; Fluticasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Patient Education as Topic; Pregnenediones | 2001 |
The efficacy and safety of QVAR (hydrofluoroalkane-beclometasone diproprionate extrafine aerosol) in asthma (part 1): an update of clinical experience in adults.
Topics: Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Double-Blind Method; Fluticasone; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Multicenter Studies as Topic; Peak Expiratory Flow Rate; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2004 |
Pharmacokinetic and pharmacodynamic properties of inhaled beclometasone dipropionate delivered via hydrofluoroalkane-containing devices.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2005 |
Beclomethasone dipropionate hydrofluoroalkane for the treatment of allergic rhinitis.
Topics: Adult; Aerosol Propellants; Animals; Anti-Asthmatic Agents; Beclomethasone; Child; Humans; Hydrocarbons, Fluorinated; Medication Adherence; Nasal Sprays; Quality of Life; Rhinitis, Allergic | 2016 |
Extrafine HFA-beclomethasone-formoterol vs. nonextrafine combination of an inhaled corticosteroid and a long acting β2-agonist in patients with persistent asthma: A systematic review and meta-analysis.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Adult; Aged; Asthma; Beclomethasone; Female; Formoterol Fumarate; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Outcome Assessment, Health Care; Publication Bias; Risk; Young Adult | 2021 |
50 trial(s) available for apaflurane and (9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
| Article | Year |
|---|---|
Efficacy of chlorofluorocarbon-free beclomethasone dipropionate 400 micrograms day-1 delivered as an extrafine aerosol in adults with moderate asthma.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Aerosols; Anti-Inflammatory Agents; Beclomethasone; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydrocarbons, Fluorinated; Male; Particle Size | 1998 |
Hydrofluoroalkane-134a beclomethasone dipropionate extrafine aerosol provides equivalent asthma control to chlorofluorocarbon beclomethasone dipropionate at approximately half the total daily dose.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Aerosol Propellants; Aerosols; Aged; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Middle Aged | 1998 |
Safety of hydrofluoroalkane-134a beclomethasone dipropionate extrafine aerosol.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Cosyntropin; Cough; Cross-Over Studies; Drug Administration Schedule; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Hypothalamo-Hypophyseal System; Middle Aged; Pituitary-Adrenal System | 1998 |
Hydrofluoroalkane-134a beclomethasone dipropionate, 400 microg, is as effective as chlorofluorocarbon beclomethasone dipropionate, 800 microg, for the treatment of moderate asthma.
Topics: Adult; Aerosols; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Drug Combinations; Female; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Male; Peak Expiratory Flow Rate; Treatment Outcome | 1999 |
Adrenal effects and pharmacokinetics of CFC-free beclomethasone dipropionate: a 14-day dose-response study.
Topics: Administration, Inhalation; Adrenal Glands; Anti-Asthmatic Agents; Asthma; Beclomethasone; Biological Availability; Chlorofluorocarbons; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Nebulizers and Vaporizers; Particle Size; Placebos; Smoking | 1999 |
Acute safety of beclomethasone dipropionate in a new CFC-free propellant system in asthmatic patients.
Topics: Administration, Topical; Adult; Aerosol Propellants; Aged; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchi; Cross-Over Studies; Drug Evaluation; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Single-Blind Method | 1999 |
Inhaled beclomethasone (BDP) with non-CFC propellant (HFA 134a) is equivalent to BDP-CFC for the treatment of asthma.
Topics: Adolescent; Adult; Aerosol Propellants; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Nebulizers and Vaporizers; Treatment Outcome | 1999 |
Health-related quality of life in moderate asthma: 400 microg hydrofluoroalkane beclomethasone dipropionate vs 800 microg chlorofluorocarbon beclomethasone dipropionate. The Study Group.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Asthma; Beclomethasone; Chlorofluorocarbons; Drug Combinations; Female; Forced Expiratory Volume; Health Status; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Patient Compliance; Peak Expiratory Flow Rate; Quality of Life; Safety; Surveys and Questionnaires; Treatment Outcome | 1999 |
Comparative effects of hydrofluoroalkane and chlorofluorocarbon beclomethasone dipropionate inhalation on small airways: assessment with functional helical thin-section computed tomography.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Asthma; Beclomethasone; Bronchial Provocation Tests; Chlorofluorocarbons; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Image Processing, Computer-Assisted; Lung; Male; Middle Aged; Peak Expiratory Flow Rate; Pilot Projects; Respiratory Function Tests; Spirometry; Tomography Scanners, X-Ray Computed | 1999 |
Pharmacokinetics of chlorofluorocarbon and hydrofluoroalkane metered-dose inhaler formulations of beclomethasone dipropionate.
Topics: Adult; Aerosol Propellants; Anti-Inflammatory Agents; Area Under Curve; Beclomethasone; Biological Availability; Chlorofluorocarbons; Cross-Over Studies; Female; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Nebulizers and Vaporizers | 1999 |
Therapeutic equivalence of inhaled beclomethasone dipropionate with CFC and non-CFC (HFA 134a) propellants both delivered via the Easibreathe inhaler for the treatment of paediatric asthma.
Topics: Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Chlorofluorocarbons; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Nebulizers and Vaporizers; Therapeutic Equivalency; Treatment Outcome | 2000 |
Equivalent asthma control after dose reduction with HFA-134a beclomethasone solution aerosol. Comparative Inhaled Steroid Investigation Group (CISIG).
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Patient Compliance; Peak Expiratory Flow Rate; Reproducibility of Results | 2000 |
Efficacy of HFA-beclomethasone dipropionate extra-fine aerosol (800 microg day(-1)) versus HFA-fluticasone propionate (1000 microg day(-1)) in patients with asthma.
Topics: Adolescent; Adult; Aerosol Propellants; Aged; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Eosinophils; Equipment Design; Female; Fluticasone; Humans; Hydrocarbons, Fluorinated; Leukocyte Count; Male; Middle Aged; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Treatment Outcome | 2001 |
Long-term safety and efficacy of a chlorofluorocarbon-free beclomethasone dipropionate extrafine aerosol.
Topics: Administration, Inhalation; Adolescent; Adrenergic beta-Antagonists; Adult; Aerosol Propellants; Aerosols; Anti-Asthmatic Agents; Beclomethasone; Biomarkers; Chlorofluorocarbons; Depression; Drug Eruptions; Drug Therapy, Combination; Edema; Female; Forced Expiratory Volume; Gingivitis; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Nebulizers and Vaporizers; Osteocalcin; Pain; Particle Size; Peak Expiratory Flow Rate; Respiratory Tract Diseases; Safety; Treatment Outcome; Vomiting | 2001 |
Asthma stability after oral prednisone: a clinical model for comparing inhaled steroid potency.
Topics: Administration, Inhalation; Administration, Oral; Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Male; Peak Expiratory Flow Rate; Prednisone | 2001 |
Comparison of hydrofluoroalkane-beclomethasone dipropionate Autohaler with budesonide Turbuhaler in asthma control.
Topics: Administration, Inhalation; Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Asthma; Beclomethasone; Blood Proteins; Budesonide; Cohort Studies; Creatinine; Eosinophil Granule Proteins; Eosinophils; Female; Follow-Up Studies; Forced Expiratory Volume; France; Germany; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Leukocyte Count; Male; Middle Aged; Netherlands; Peak Expiratory Flow Rate; Respiratory Function Tests; Ribonucleases; Treatment Outcome | 2001 |
Growth, systemic safety, and efficacy during 1 year of asthma treatment with different beclomethasone dipropionate formulations: an open-label, randomized comparison of extrafine and conventional aerosols in children.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Budesonide; Chemistry, Pharmaceutical; Child; Child Development; Child, Preschool; Chlorofluorocarbons; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Growth; Humans; Hydrocarbons, Fluorinated; Male; Respiratory Function Tests; Treatment Outcome | 2002 |
Step-down therapy with low-dose fluticasone-salmeterol combination or medium-dose hydrofluoroalkane 134a-beclomethasone alone.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Albuterol; Androstadienes; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchial Provocation Tests; Bronchodilator Agents; Drug Administration Schedule; Drug Therapy, Combination; Fluticasone; Humans; Hydrocarbons, Fluorinated; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Respiratory Function Tests; Salmeterol Xinafoate | 2002 |
Switching from conventional to extrafine aerosol beclomethasone dipropionate therapy in children: a 6-month, open- label, randomized trial.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Chlorofluorocarbons; Drug Administration Schedule; Female; Humans; Hydrocarbons, Fluorinated; Male; Patient Compliance; Treatment Outcome | 2002 |
The cost effectiveness of chlorofluorocarbon-free beclomethasone dipropionate in the treatment of chronic asthma: a cost model based on a 1-year pragmatic, randomised clinical study.
Topics: Asthma; Beclomethasone; Chlorofluorocarbons; Chronic Disease; Cost-Benefit Analysis; Humans; Hydrocarbons, Fluorinated; Prospective Studies; Quality of Life; Treatment Outcome | 2002 |
Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone : a cross-over study in healthy volunteers.
Topics: Administration, Inhalation; Administration, Topical; Adult; Aerosol Propellants; Aerosols; Androstadienes; Anti-Inflammatory Agents; Beclomethasone; Chlorofluorocarbons; Cross-Over Studies; Female; Fluticasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Lung; Male; Middle Aged; Particle Size; Radionuclide Imaging; Radiopharmaceuticals; Technetium | 2002 |
Modulite technology: pharmacodynamic and pharmacokinetic implications.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Budesonide; Chemistry, Pharmaceutical; Cross-Over Studies; Double-Blind Method; Drug Delivery Systems; Female; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Nebulizers and Vaporizers; Therapeutic Equivalency | 2002 |
Airway and systemic effects of hydrofluoroalkane fluticasone and beclomethasone in patients with asthma.
Topics: Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchoconstrictor Agents; Bronchodilator Agents; Creatinine; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Fluticasone; Forced Expiratory Flow Rates; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Methacholine Chloride | 2002 |
Equivalent efficacy and safety of a new HFA-134a formulation of BDP compared with the conventional CFC in adult asthmatics.
Topics: Adult; Aged; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Budesonide; Chemistry, Pharmaceutical; Chlorofluorocarbons; Double-Blind Method; Female; Fluticasone; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Least-Squares Analysis; Male; Middle Aged; Patient Compliance; Peak Expiratory Flow Rate; Severity of Illness Index; Treatment Outcome; United Kingdom; Vital Capacity | 2002 |
A new HFA-134a propellant in the administration of inhaled BDP via the Jet spacer: controlled clinical trial vs the conventional CFC.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aerosols; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Female; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Middle Aged; Peak Expiratory Flow Rate; Respiratory Mechanics; Treatment Outcome | 2002 |
Effects on lung function, symptoms, and bronchial hyperreactivity of low-dose inhaled beclomethasone dipropionate given with HFA-134a or CFC propellant.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Aerosols; Analysis of Variance; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchial Hyperreactivity; Chlorofluorocarbons; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Nebulizers and Vaporizers; Respiratory Function Tests | 2002 |
Hydrofluoroalkane-134a beclomethasone as a dominant economic asthma therapy.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Cost-Benefit Analysis; Drug Costs; Female; Forced Expiratory Volume; Health Resources; Humans; Hydrocarbons, Fluorinated; Male | 2003 |
Safety and efficacy of HFA-134a beclomethasone dipropionate extra-fine aerosol over six months.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Drug Administration Schedule; Female; Headache; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Respiratory Tract Infections; Treatment Outcome | 2004 |
Direct measurement of BDP and 17-BMP in bronchial and peripheral lung tissue after inhalation of HFA- vs CFC-driven aerosols.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Aged; Beclomethasone; Bronchi; Chlorofluorocarbons; Drug Carriers; Female; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Lung; Male; Middle Aged; Particle Size; Time Factors; Tissue Distribution | 2004 |
Effects of HFA- and CFC-beclomethasone dipropionate on the bronchial response to methacholine (MCh) in mild asthma.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchi; Bronchoconstrictor Agents; Chlorofluorocarbons; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Male; Metered Dose Inhalers; Methacholine Chloride; Middle Aged; Respiratory Function Tests | 2005 |
Hydrofluoroalkane-134A beclomethasone or chlorofluorocarbon fluticasone: effect on small airways in poorly controlled asthma.
Topics: Administration, Inhalation; Adult; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchi; Bronchodilator Agents; Chlorofluorocarbons; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluticasone; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Pharmaceutical Solutions; Pulmonary Ventilation; Single-Blind Method; Suspensions | 2005 |
Effects of hydrofluoroalkane and dry powder-formulated corticosteroids on sputum inflammatory markers in asthmatic patients.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Aerosol Propellants; Algorithms; Anti-Asthmatic Agents; Asthma; Beclomethasone; Biomarkers; Budesonide; Cytokines; Double-Blind Method; Eosinophils; Female; Humans; Hydrocarbons, Fluorinated; Lymphocytes; Male; Powders; Sputum | 2006 |
A comparison of 2 extrafine hydrofluoroalkane-134a-beclomethasone formulations on methacholine hyperresponsiveness.
Topics: Adolescent; Adult; Aerosol Propellants; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Creatine; Female; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Methacholine Chloride; Middle Aged; Nitric Oxide; Spirometry; Therapeutic Equivalency; Treatment Outcome | 2006 |
Usefulness of HFA-BDP for adult patients with bronchial asthma: randomized crossover study with fluticasone.
Topics: Adrenergic beta-Agonists; Adult; Aerosol Propellants; Androstadienes; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Bronchodilator Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Fluticasone; Humans; Hydrocarbons, Fluorinated; Male; Medical Records; Metered Dose Inhalers; Middle Aged; Particle Size; Peak Expiratory Flow Rate | 2006 |
Short-term growth and adrenal function in children with asthma treated with inhaled beclomethasone dipropionate hydrofluoroalkane-134a.
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Chlorofluorocarbons; Chlorofluorocarbons, Methane; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Hypothalamo-Hypophyseal System; Leg; Male; Pituitary-Adrenal System; Treatment Outcome | 2006 |
Differential anti-inflammatory effects of large and small particle size inhaled corticosteroids in asthma.
Topics: Acetates; Administration, Inhalation; Adrenal Cortex Hormones; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Cyclopropanes; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Eosinophils; Humans; Hydrocarbons, Fluorinated; Inflammation; Nitric Oxide; Particle Size; Quinolines; Sulfides | 2007 |
An in vivo and in vitro comparison of inhaled steroid delivery via a novel vortex actuator and a conventional valved holding chamber.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Nebulizers and Vaporizers | 2007 |
Efficacy and safety of inhaled ciclesonide compared with chlorofluorocarbon beclomethasone dipropionate in adults with moderate to severe persistent asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Beclomethasone; Female; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Pregnenediones | 2007 |
[A multicenter, open-label, randomized comparison of suppressive effects on asthmatic inflammation of lower airways and improved effects on health-related QOL between HFA-BDP and fluticasone propionate].
Topics: Administration, Inhalation; Aerosol Propellants; Aged; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchodilator Agents; Fluticasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Middle Aged; Quality of Life | 2007 |
Clinical efficacy of short-term treatment with extra-fine HFA beclomethasone dipropionate in patients with post-infectious persistent cough.
Topics: Acute Disease; Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aerosol Propellants; Antitussive Agents; Beclomethasone; Chemistry, Pharmaceutical; Cough; Double-Blind Method; Drug Administration Schedule; Female; Germany; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Patient Compliance; Powders; Respiratory Tract Infections; Treatment Outcome | 2007 |
Efficacy and safety of once or twice daily inhalation of extrafine HFA beclomethasone dipropionate in patients with mild to moderate asthma.
Topics: Administration, Inhalation; Adolescent; Adrenal Cortex Hormones; Adult; Aerosol Propellants; Aged; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Germany; Humans; Hydrocarbons, Fluorinated; Male; Middle Aged; Powders; Severity of Illness Index; Treatment Outcome | 2007 |
Comparison of the anti-inflammatory effects of extra-fine hydrofluoroalkane-beclomethasone vs fluticasone dry powder inhaler on exhaled inflammatory markers in childhood asthma.
Topics: Administration, Inhalation; Androstadienes; Anti-Inflammatory Agents; Asthma; Beclomethasone; Biomarkers; Breath Tests; Child; Cross-Over Studies; Dinoprost; Female; Fluticasone; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Hydrogen Peroxide; Inflammation; Interleukins; Male; Nitrates; Nitric Oxide; Nitrites; Prospective Studies; Treatment Outcome; Vital Capacity | 2008 |
The effect of high dose inhaled corticosteroids on wheeze in infants after respiratory syncytial virus infection: randomised double blind placebo controlled trial.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Beclomethasone; Child, Preschool; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Infant; Male; Metered Dose Inhalers; Poisson Distribution; Quality of Life; Respiratory Sounds; Respiratory Syncytial Virus Infections; Treatment Outcome | 2009 |
The usefulness of inspiratory flow rate during inhalation corticosteroid therapy in asthma.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Androstadienes; Asthma; Beclomethasone; Bronchodilator Agents; Budesonide; Female; Fluticasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Inhalation; Male; Middle Aged; Respiratory Function Tests | 2009 |
Effect of inhaled corticosteroids on small airways in asthma: investigation using impulse oscillometry.
Topics: Adrenal Cortex Hormones; Adult; Airway Resistance; Asthma; Beclomethasone; Chlorofluorocarbons; Double-Blind Method; Female; Humans; Hydrocarbons, Fluorinated; Lung Volume Measurements; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Nebulizers and Vaporizers; Oscillometry; Respiratory Function Tests; Respiratory System; Spirometry | 2009 |
Systemic exposure and implications for lung deposition with an extra-fine hydrofluoroalkane beclometasone dipropionate/formoterol fixed combination.
Topics: Administration, Inhalation; Adult; Beclomethasone; Cross-Over Studies; Drug Combinations; Ethanolamines; Formoterol Fumarate; Humans; Hydrocarbons, Fluorinated; Lung; Male; Middle Aged; Particle Size; Young Adult | 2009 |
Lung function changes in asthmatic children treated with HFA-BDP.
Topics: Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Chronic Disease; Female; Humans; Hydrocarbons, Fluorinated; Lung; Male; Respiratory Function Tests; Retrospective Studies | 2011 |
Short-term lower leg growth in 5- to 11-year-old asthmatic children using beclomethasone dipropionate inhalers with chlorofluorocarbon or hydrofluoroalkane propellants: a 9-week, open-label, randomized, crossover, noninferiority study.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Chlorofluorocarbons; Cross-Over Studies; Female; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Leg; Male; Metered Dose Inhalers; Treatment Outcome | 2011 |
The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma.
Topics: Adult; Asthma; Beclomethasone; Bronchial Provocation Tests; Creatinine; DNA-Binding Proteins; Double-Blind Method; Eosinophilia; Female; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Male; Nuclear Proteins; Potassium; Propranolol; Transcription Factors | 2014 |
Nasal Deposition of HFA-Beclomethasone, Aqueous Fluticasone Propionate and Aqueous Mometasone Furoate in Allergic Rhinitis Patients.
Topics: Adult; Aerosol Propellants; Aerosols; Beclomethasone; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Fluticasone; Humans; Hydrocarbons, Fluorinated; Middle Aged; Mometasone Furoate; Nasal Mucosa; Rhinitis, Allergic; Tomography, Emission-Computed, Single-Photon | 2015 |
47 other study(ies) available for apaflurane and (9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
| Article | Year |
|---|---|
Extra-fine corticosteroid aerosols from hydrofluoroalkane-134a metered-dose inhalers: potential advantages and disadvantages.
Topics: Aerosols; Anti-Asthmatic Agents; Beclomethasone; Chlorofluorocarbons; Drug Combinations; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers; Particle Size | 1999 |
Inhaled beclomethasone dipropionate symposium.
Topics: Aerosol Propellants; Beclomethasone; Chlorofluorocarbons; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Lung; Nebulizers and Vaporizers; Radioimmunodetection | 1999 |
Extra fine hydrofluoroalkane-134A beclomethasone aerosols: selecting an optimal inhaled steroid for an individual patient.
Topics: Aerosols; Asthma; Beclomethasone; Humans; Hydrocarbons, Fluorinated; Particle Size | 1999 |
The pharmacokinetics of inhaled hydrofluoroalkane formulations.
Topics: Administration, Inhalation; Aerosol Propellants; Albuterol; Beclomethasone; Chemistry, Pharmaceutical; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Lung; Radionuclide Imaging | 1999 |
Effect of formulation parameters on hydrofluoroalkane-beclomethasone dipropionate drug deposition in humans.
Topics: Beclomethasone; Chemistry, Pharmaceutical; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers; Particle Size; Patient Education as Topic | 1999 |
Equivalence of hydrofluoroalkane (HFA) and chlorofluorocarbons (CFC) formulations of inhaled beclomethasone.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2000 |
Is inhaled beclomethasone (BDP) with a non-CFC propellant equivalent to the CFC propellant formulations?
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2000 |
Inhaled beclomethasone (BDP) with non-CFC propellant (HFA-134a) is equivalent to BDP-CFC for the treatment of asthma: Milanowski et al. (Respir Med 1999; 93: 245-251)
Topics: Anti-Asthmatic Agents; Asthma; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2000 |
Inhaled beclomethasone (BDP) with non-CFC propellant (HFA 134a) is equivalent to BDP-CFC for the treatment of asthma (Respir Med 1999; 93: 245-251)
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Therapeutic Equivalency | 2000 |
Moisture uptake and its influence on pressurized metered-dose inhalers.
Topics: Beclomethasone; Chlorofluorocarbons, Methane; Chromatography, High Pressure Liquid; Drug Stability; Humidity; Hydrocarbons, Fluorinated; Models, Chemical; Nebulizers and Vaporizers; Particle Size; Time Factors; Triamcinolone Acetonide; Water | 2000 |
[New propellant for inhaled corticoids. Deeper into the alveoli].
Topics: Administration, Inhalation; Administration, Topical; Aerosol Propellants; Anti-Inflammatory Agents; Beclomethasone; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Pulmonary Alveoli | 1999 |
Influence of water on the solubility of two steroid drugs in hydrofluoroalkane (HFA) propellants.
Topics: Aerosol Propellants; Beclomethasone; Glucocorticoids; Hydrocarbons, Fluorinated; Solubility; Temperature; Triamcinolone Acetonide; Water | 2001 |
Clinical studies in asthmatics with a new non-extra fine HFA formulation of beclometasone dipropionate (BDP Modulite).
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Aerosols; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Chlorofluorocarbons; Double-Blind Method; Forced Expiratory Volume; Humans; Hydrocarbons, Fluorinated; Hydrocortisone; Maximal Midexpiratory Flow Rate; Multicenter Studies as Topic; Nebulizers and Vaporizers; Peak Expiratory Flow Rate; Randomized Controlled Trials as Topic; Therapeutic Equivalency; Vital Capacity | 2002 |
[Bronchial asthma. Small bronchi are not spared].
Topics: Aerosol Propellants; Airway Resistance; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchi; Dose-Response Relationship, Drug; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers | 2002 |
A neglected breakthrough in asthma therapy.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Inflammatory Agents; Asthma; Beclomethasone; Child; Drug Combinations; Eosinophils; Humans; Hydrocarbons, Fluorinated; Patient Selection; Predictive Value of Tests; Sputum; Treatment Outcome | 2003 |
Local versus total systemic bioavailability of beclomethasone dipropionate CFC and HFA metered dose inhaler formulations.
Topics: Administration, Inhalation; Aerosol Propellants; Aerosols; Anti-Asthmatic Agents; Area Under Curve; Beclomethasone; Biological Availability; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers | 2002 |
Extra-fine particles improve lung delivery of inhaled steroids in infants: a study in an upper airway model.
Topics: Administration, Inhalation; Aerosol Propellants; Beclomethasone; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Infant; Lung; Metered Dose Inhalers; Models, Anatomic; Particle Size; Steroids | 2003 |
Balancing ethanol cosolvent concentration with product performance in 134a-based pressurized metered dose inhalers.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Asthmatic Agents; Beclomethasone; Chromatography, High Pressure Liquid; Ethanol; Humans; Hydrocarbons, Fluorinated; Nebulizers and Vaporizers; Particle Size; Pressure; Solubility | 2003 |
In vitro performance of two common valved holding chambers with a chlorofluorocarbon-free beclomethasone metered-dose inhaler.
Topics: Aerosol Propellants; Anti-Asthmatic Agents; Beclomethasone; Equipment Design; Hydrocarbons, Fluorinated; Metered Dose Inhalers | 2003 |
HFA inhalers.
Topics: Aerosol Propellants; Albuterol; Asthma; Beclomethasone; Bronchodilator Agents; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic | 2004 |
Sub-micrometer particle production by pressurized metered dose inhalers.
Topics: Aerosol Propellants; Aerosols; Beclomethasone; Chlorofluorocarbons; Glucocorticoids; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Particle Size | 2004 |
Hydrofluoroalkane-beclomethasone versus chlorofluorocarbon-beclomethasone delivery in neonatal models.
Topics: Administration, Inhalation; Aerosol Propellants; Aerosols; Beclomethasone; Chemistry, Pharmaceutical; Chlorofluorocarbons; Drug Delivery Systems; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Infant, Newborn; Intubation, Intratracheal; Masks; Nebulizers and Vaporizers; Respiration, Artificial | 2004 |
The efficacy and safety of QVAR (hydrofluoroalkane-beclometasone diproprionate extrafine aerosol) in asthma (Part 2): Clinical experience in children.
Topics: Administration, Inhalation; Aerosol Propellants; Aerosols; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Humans; Hydrocarbons, Fluorinated; Lung; Treatment Outcome | 2004 |
Successful treatment of hypersensitivity pneumonitis caused by Grifola frondosa (Maitake) mushroom using a HFA-BDP extra-fine aerosol.
Topics: Administration, Inhalation; Aerosol Propellants; Agaricales; Agricultural Workers' Diseases; Alveolitis, Extrinsic Allergic; Beclomethasone; Female; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Middle Aged; Spores, Fungal | 2004 |
Application of USP inlet extensions to the TSI impactor system 3306/3320 using HFA 227 based solution metered dose inhalers.
Topics: Aerosol Propellants; Algorithms; Anti-Asthmatic Agents; Beclomethasone; Chemistry, Pharmaceutical; Drug Compounding; Ethanol; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Particle Size; Pharmaceutical Solutions; Pharmacopoeias as Topic; Solutions; Solvents; United States | 2005 |
Manipulation of beclomethasone-hydrofluoroalkane interactions using biocompatible macromolecules.
Topics: Aerosol Propellants; Algorithms; Anti-Inflammatory Agents; Beclomethasone; Biocompatible Materials; Chemical Phenomena; Chemistry, Physical; Drug Stability; Electrochemistry; Excipients; Hyaluronic Acid; Hydrocarbons, Fluorinated; Microscopy, Electron, Scanning; Polyvinyl Alcohol; Povidone; Solvents | 2006 |
One-year evaluation of the preventative effect of hydrofluoroalkane-beclomethasone dipropionate on eosinophilic inflammation of asthmatic peripheral airways.
Topics: Administration, Inhalation; Aerosol Propellants; Aged; Asthma; Beclomethasone; Bronchitis; Eosinophilia; Eosinophils; Female; Follow-Up Studies; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Leukocyte Count; Male; Middle Aged; Sputum; Time Factors; Treatment Outcome; Vital Capacity | 2007 |
Pharmacokinetics of beclomethasone dipropionate in an hydrofluoroalkane-134a propellant system in Japanese children with bronchial asthma.
Topics: Adolescent; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Female; Humans; Hydrocarbons, Fluorinated; Japan; Male; United States | 2006 |
Lung deposition of HFA beclomethasone dipropionate in an animal model of bronchopulmonary dysplasia.
Topics: Aerosol Propellants; Animals; Animals, Newborn; Beclomethasone; Bronchopulmonary Dysplasia; Disease Models, Animal; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Infant, Newborn; Lung; Male; Swine | 2007 |
[Influence of changing from chlorofluorocarbon (CFC)-beclomethasone dipropionate (BDP) to hydrofluoroalkane (HFA)-BDP on pulmonary function in asthmatic children].
Topics: Administration, Inhalation; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Chlorofluorocarbons; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Male | 2007 |
Determining degree of saturation after application of transiently supersaturated metered dose aerosols for topical delivery of corticosteroids.
Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Aerosols; Beclomethasone; Betamethasone Valerate; Cellulose; Chemistry, Pharmaceutical; Diffusion; Ethanol; Hydrocarbons, Fluorinated; Kinetics; Membranes, Artificial; Models, Chemical; Povidone; Silicones; Solubility; Solvents; Thermodynamics; Volatilization | 2009 |
Manipulation of corticosteroid release from a transiently supersaturated topical metered dose aerosol using a residual miscible co-solvent.
Topics: Aerosols; Beclomethasone; Ethanol; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Polyethylene Glycols; Povidone; Solubility | 2008 |
Transient drug supersaturation kinetics of beclomethasone dipropionate in rapidly drying films.
Topics: Administration, Cutaneous; Aerosols; Beclomethasone; Chromatography, High Pressure Liquid; Crystallization; Drug Carriers; Drug Delivery Systems; Hydrocarbons, Fluorinated; Kinetics; Models, Theoretical; Povidone; Solubility; Solvents; Volatilization | 2009 |
Analysis of inhaled corticosteroid selection in patients with bronchial asthma using a questionnaire survey--effects of age, gender, and disease severity.
Topics: Administration, Inhalation; Age Factors; Androstadienes; Asthma; Beclomethasone; Bronchodilator Agents; Budesonide; Drug Prescriptions; Female; Fluticasone; Humans; Hydrocarbons, Fluorinated; Japan; Male; Middle Aged; Retrospective Studies; Sex Factors; Surveys and Questionnaires; Treatment Outcome | 2009 |
A pilot study to assess lung deposition of HFA-beclomethasone and CFC-beclomethasone from a pressurized metered dose inhaler with and without add-on spacers and using varying breathhold times.
Topics: Administration, Inhalation; Adult; Aerosol Propellants; Anti-Inflammatory Agents; Beclomethasone; Chlorofluorocarbons; Humans; Hydrocarbons, Fluorinated; Lung; Male; Metered Dose Inhalers; Middle Aged; Particle Size; Pilot Projects; Respiration; Technetium | 2010 |
Asthma control with extrafine-particle hydrofluoroalkane-beclometasone vs. large-particle chlorofluorocarbon-beclometasone: a real-world observational study.
Topics: Adolescent; Adult; Aerosol Propellants; Anti-Asthmatic Agents; Asthma; Beclomethasone; Child; Child, Preschool; Chlorofluorocarbons; Cohort Studies; Female; Humans; Hydrocarbons, Fluorinated; Male; Metered Dose Inhalers; Middle Aged; Particle Size; Risk Factors; Treatment Outcome; Young Adult | 2011 |
Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane-134a beclomethasone in asthmatic patients.
Topics: Administration, Inhalation; Aerosol Propellants; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Cross-Over Studies; Drug Combinations; Fluticasone-Salmeterol Drug Combination; Humans; Hydrocarbons, Fluorinated; Lung; Particle Size; Radionuclide Imaging | 2012 |
Influence of dentures on residual inhaled corticosteroids in the mouths of elderly asthma patients.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Androstadienes; Asthma; Beclomethasone; Bronchodilator Agents; Candidiasis, Oral; Dentures; Female; Fluticasone; Humans; Hydrocarbons, Fluorinated; Male; Mouth; Mouthwashes | 2012 |
In vitro investigation of the effect of ambient humidity on regional delivered dose with solution and suspension MDIs.
Topics: Administration, Inhalation; Aerosol Propellants; Androstadienes; Beclomethasone; Bronchodilator Agents; Chemistry, Pharmaceutical; Drug Delivery Systems; Ethanol; Fluticasone; Glucocorticoids; Glycerol; Humans; Humidity; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Models, Anatomic; Mouth; Pharynx; Rheology; Temperature | 2013 |
In brief: two intranasal corticosteroid HFA aerosols for allergic rhinitis.
Topics: Administration, Intranasal; Aerosol Propellants; Aerosols; Anti-Allergic Agents; Beclomethasone; Drug Approval; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; Pregnenediones; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; United States; United States Food and Drug Administration | 2012 |
Asthma outcomes and costs of therapy with extrafine beclomethasone and fluticasone.
Topics: Adult; Androstadienes; Anti-Asthmatic Agents; Asthma; Beclomethasone; Bronchodilator Agents; Cohort Studies; Female; Fluticasone; Health Care Costs; Humans; Hydrocarbons, Fluorinated; Male; Metered Dose Inhalers; Middle Aged; Retrospective Studies | 2013 |
Topical corticosteroid delivery into human skin using hydrofluoroalkane metered dose aerosol sprays.
Topics: Administration, Topical; Aerosol Propellants; Aerosols; Beclomethasone; Betamethasone Valerate; Ethanol; Glucocorticoids; Humans; Hydrocarbons, Fluorinated; In Vitro Techniques; Metered Dose Inhalers; Myristates; Polyethylene Glycols; Polyvinyls; Pyrrolidines; Skin; Solvents | 2013 |
Isothermal calorimetry: a predictive tool to model drug-propellant interactions in pressurized metered dose systems.
Topics: Aerosol Propellants; Albuterol; Beclomethasone; Calorimetry; Chemistry, Pharmaceutical; Crystallization; Fluorocarbons; Hydrocarbons, Fluorinated; Metered Dose Inhalers | 2014 |
Isothermal microcalorimetry of pressurized systems I: a rapid method to evaluate pressurized metered dose inhaler formulations.
Topics: Aerosol Propellants; Beclomethasone; Calorimetry; Crystallization; Drug Stability; Equipment Design; Ethanolamines; Formoterol Fumarate; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Microscopy, Electron, Scanning; Surface Properties | 2014 |
The effect of actuator nozzle designs on the electrostatic charge generated in pressurised metered dose inhaler aerosols.
Topics: Aerosol Propellants; Aerosols; Aluminum; Beclomethasone; Equipment Design; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Polyethylene Terephthalates; Polytetrafluoroethylene; Static Electricity | 2015 |
Humidity affects the morphology of particles emitted from beclomethasone dipropionate pressurized metered dose inhalers.
Topics: Aerosols; Beclomethasone; Ethanol; Humidity; Hydrocarbons, Fluorinated; Metered Dose Inhalers; Particle Size; Pressure | 2017 |
Bioavailability of Beclometasone From Two HFA-BDP Formulations With a Spacer.
Topics: Aerosol Propellants; Aged; Anti-Asthmatic Agents; Beclomethasone; Biological Availability; Drug Delivery Systems; Female; Humans; Hydrocarbons, Fluorinated; Inhalation Spacers; Male; Middle Aged | 2019 |